Officers are still trying to determine why Paddock, 64, opened fire on a concert from the Mandalay Bay Hotel.
However, they do know there was a high degree of planning.
The authorities in Las Vegas revised the death toll down from 59 on Tuesday evening, saying that one of the bodies was that of the gunman.
Clark County Sheriff Joseph Lombardo told reporters: "This individual was pre-meditated. Obviously pre-meditated, the fact that he had the type of weaponry and the amount of weaponry in that room.
"It was pre-planned extensively and I'm pretty sure he evaluated everything he did in his actions."
Undersheriff Kevin McMahill suggested the attack may have stopped when Paddock was disturbed, shooting a security guard.
The shooting - the worst in modern US history - has sparked debate over US gun laws, but President Donald Trump has said the discussion over what, if anything, needs to be done was "not for now".
He earlier described Paddock as "a sick man, a demented man".
But a senior US homeland security official, speaking on condition of anonymity to news agency Reuters, said there was "no evidence" of "mental illness or brain damage".
Nor have police found links to any foreign or domestic terrorist organisations.
Paddock, who appears to have killed himself before police stormed his hotel room, had no criminal record and was not known to police.
However, police found 23 guns in Paddock's hotel room, as well as firearms and explosives at his home. In total, across three locations, 47 firearms have been recovered, officials said.
Photos from the hotel room of guns used in the attack have been obtained by Boston 25 News.
Police still consider the woman thought to have been his girlfriend, Marilou Danley, "a person of interest", he said, adding they were "in conversation".
Ms Danley had been in the Philippines, but flew out of the country, the Philippine immigration bureau spokeswoman told reporters and has now arrived in Los Angeles.
The shooting has prompted calls for reform to US gun laws.
But Mr Trump - who has been backed by the National Rifle Association, and spoke often of protecting the Second Amendment during his campaign - has tried to steer clear of leaning too far either way.
After visiting Puerto Rico on Tuesday, he said "perhaps that [time] will come" for a debate.
Earlier, he had said: "We'll be talking about gun laws as time goes by."
Mr Trump, whose position on gun control has changed over the years, gave no further detail.
Mr Trump also declined to call the attack domestic terrorism.
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