One seriously injured person was resuscitated at the scene, but later died of his injuries either on the way to the hospital or at the hospital, a fire department spokesman said.
More than 250 other passengers on board the Intercity express (ICE) train were uninjured.
Police called for buses to transport them from the scene of the crash, local media reported.
The intercity express (ICE) train was headed to the northwestern city of Bremen when it crashed into a truck loaded with railroad tracks at a crossing in Hamburg's Rönneburg district. The load was scattered across the scene.
A woman on board the train told Germany's DPA news agency that the train suddenly braked hard, which was followed by an loud impact.
The line between Hamburg-Harburg and Maschen in Lower Saxony was temporarily closed and other trains were diverted.
AzVision.az