A spokesperson said he passed away in his sleep after suffering a seizure.
He made his acting debut in the horror film Mirrors but it best known for roles in Disney's Descendants and the TV show Jessie.
His death was confirmed on the evening of Saturday 6 July and linked to "an ongoing medical condition".
"It is with a profoundly heavy heart that we report that this morning we lost Cameron," a spokesperson said on behalf of his family.
"He passed away in his sleep due to a seizure which was a result of an ongoing medical condition for which he was being treated.
"The world is now undoubtedly without one of its brightest lights, but his spirit will live on through the kindness and compassion of all who knew and loved him.
"We are utterly heartbroken and ask for privacy during this immensely difficult time as we grieve the loss of our precious son and brother."
Cameron Boyce was only nine years old when he appeared in Mirrors. He then went on to play one of Adam Sandler's children in the movie Grown Ups.
However it was on the Disney channel show Jessie that he became most well known as the character Luke Ross.
That led to him playing the part of Carlos de Vil in Descendants, the popular TV movie series which follows the lives of the children of Disney baddies.
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