AFAD said the quake struck Manisa's Kırkağaç district at 2:26 p.m. local time (1126 GMT) from a depth of 6.99 kilometers.
According to initial reports, the tremor was felt from neighboring provinces, including İzmir, Aydın and Denizli.
In a statement, Manisa Governorate said no casualties or damages have been reported so far.
The tremor caused panic among locals as it came four days after a major magnitude 6.8 earthquake rocked the eastern province of Elazığ, killing at least 41 people and injuring 1,607 others. The earthquake also destroyed dozens of buildings in Elazığ and the neighboring Manisa.
Turkey is among the world's most seismically active countries as it is situated on several active fault lines, and dozens of minor earthquakes and aftershocks occur daily.
The earthquake in Elazığ was triggered by the deadly East Anatolian fault line, stretching some 650 kilometers from eastern Turkey's highlands to the Mediterranean, from where it turns southwards and meets the northern end of the Great Rift system separating African and Arabian plates.