The epidemic, which began in Guinea, has killed more than 11,000 people in West Africa. Neighbouring Sierra Leone and Liberia have already been declared Ebola-free.
"The last confirmed case of Ebola has been released from a treatment centre," said Fode Tass Sylla of the Ebola co-ordination unit.
"We did two tests after his treatment and they came back negative."
The 19-day-old baby was born in the Nongo Ebola treatment centre but his infected mother did not survive, Reuters reported.
Sierra Leone was declared Ebola-free by the World Health Organization earlier this month after 42 days without a single declared case.
Liberia was declared free of the disease in September. The Ebola outbreak in West Africa was first reported in March 2014.
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