Lab tests confirmed that the two had contracted H1N1 flu, it said.
The husband had a history of illness including pneumonia, spinal tuberculosis and kidney stones, while the wife suffered from heart disease, the commission said.
A total of 112 people, including 93 medical staff and 19 relatives, have been put under medical observation in Baiyin. Only three have shown any flu-like symptoms, two of which have been treated and the other is still showing slight symptoms.
The commission ordered Baiyin health authority to improve its monitoring system.
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