The nurse`s alleged victims had "various pathologies", police said, but no further details about the case were given. Investigators are scheduled to hold a press conference later on Thursday.
Italy`s para-military police, the Carabinieri, detained the woman late on Wednesday.
It is not the first time in recent years a nurse working for Italy`s state-funded healthcare system has been accused of being a serial killer.
Earlier this month, a court in Ravenna convicted a nurse for killing a patient with a lethal injection of potassium, handing her a life sentence. She is still under investigation for about 10 other suspicious deaths and is appealing last year`s conviction.
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