The news website Sada El-Balad cited a source in the investigation team as saying an unknown attacker threw a bomb inside the cathedral during a prayer service.
Watch: a video showing the explosion from a distance.
A dozen of ambulances have arrived at the scene of the explosion, the local news website Youm7 said. No armed group has reportedly claimed responsibility for it.
There has been no claim of responsibility yet.
Earlier reports cited Egypt`s Ministry of Health saying that five people died in the explosion and ten more were injured.
The cathedral in the Egyptian capital`s Abbassia district serves as the seat of the Coptic Orthodox Pope. Copts are a large ethnic and religious minority in Egypt.
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13:10
According to a source in the Egyptian Security, an explosion took place near Cairo`s Coptic Cathedral on Sunday, Reuters reports.
At least five people have died in the explosion and ten more have been injured, local media reports citing Egypt`s Ministry of Health.
There has been no claim of responsibility yet.
#Breaking, #Egypt:
— Jewish Breaking News (@JBN) December 11, 2016
Casualties reported after an #explosion at the Coptic Orthodox cathedral in #Cairo. pic.twitter.com/TLTpM337QL
