On Monday, Moldovan government had expelled five Russian diplomats without making the reason public.
Russian Foreign Ministry said Nikolae Miinea, the Minister-Counselor of the Moldovan Embassy, was invited to the ministry, where a note was given to him.
Russia hopes Moldova will realize its "unfriendly" actions towards Moscow are "counterproductive".
"Moldova’s latest move is destructive and runs counter to the principles of partnership and mutual confidence," the statement added.
Following Russia's move, Moldovan President Igor Dodon said on his official Twitter account: "For the 25-year history of diplomatic relations between the Republic of Moldova and Russia, our bilateral relations have never been on the brink of the abyss, as now."
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