The status of the pilot, or pilots, was not immediately clear.
In a statement, the Air Force said, “Emergency responders are on the scene. As soon as additional details become available, they will be provided. The accident is under investigation."
The jet crashed around 10:30 a.m. during routine training at Nevada Test and Training Range, officials said.
The incident marks the third crash of a U.S. military aircraft since Tuesday, when a Marine Corps CH-53E Super Stallion helicopter crashed during exercises along the U.S.-Mexico border in California, killing four crew members.
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