The online newspaper eldiario.es cites "emergency services" as saying that as well as the victim and the five injured -- one of whom is in a serious condition, six people have also been trapped.
Reports state that part of the structure on the inside of the hotel collapsed at around 16:00 hours local time as renovation work continued on the building which has been closed since February.
The area in the center of Madrid has been cordoned off, with emergency services arriving on the scene.
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