The Spanish national, who was among the ten seriously wounded people, succumbed to her injuries in the afternoon.
Two firefighters, aged 27 and 28 years, also lost their lives due to a "dramatic explosion" which happened as "they were looking for a gas leak in the building", Interior Minister Christophe Castaner said earlier on Saturday.
At least 37 others, mostly passers-by, had lighter injuries.
The explosion occurred at around 9:00 a.m. (0800 GMT) in a closed bakery on the Rue de Trevise in the 9th district of Paris due to a suspected gas leak.
Television images showed the capital's shopping district turned to a devastating site. The huge blast blew out the entire ground floor of the building, with storefronts blown out and windows shattered up to the fouth floor.
Shop windows were smashed, other buildings and parked vehicles were also damaged by the force of the blast.
More than 200 firefighters and 100 police officers have been deployed. Two helicopters also landed on the nearby Place de l'Opera to evacuate victims.
The Regional Directorate of Judicial Police has opened an investigation into the explosion.