"In the past few months, we have identified a significant increase in the scope of cyber attacks on Israel by Iran. These attacks are carried out directly by Iran and through its proxies, Hamas and Hezbollah," he told a conference on cyber warfare in his country`s commercial hub Tel Aviv.
"Despite the non-stop attacks on us, you hear only about a few of them because we thwart most of them," he added.
Netanyahu established a national cyber directorate in 2011 charged with protecting Israel`s computer systems from disruption.
Israel and the United States are widely believed to be behind a series of cyber attacks in recent years against an Iranian nuclear programme they say is aimed at developing atomic weapons. Iran says its nuclear activities are peaceful.
Two months ago, Israel said it weathered a pro-Palestinian cyber attack campaign against government websites. Israeli officials said those attacks briefly disrupted several sites and security protocols were updated in response.