The images are being shared via the hashtags #handinhand and #allemannenhandinhand (all men hand in hand).
Politicians, celebrities, football pundits and workers have joined in, throughout the Netherlands and beyond.
Danish radio and television host Mikael Bertelsen is one of the latest to take part on Instagram
Jasper Vernes-Sewratan, 35, and Ronnie Sewratan-Vernes, 31, say they were attacked by a group of men in the early hours of Sunday morning in Arnhem, in the country's east.
Their story was widely publicised and they appeared on Dutch talk show Pauw earlier this week, where they described being set upon after holding hands.
The lawyer of one of the alleged attackers also appeared on the show, later in the week, claiming the pair threw the first punch.
The couple have emphatically denied this.
Austrian politician Andreas Schieder also published a picture on Wednesday, saying homophobia has no place in Austria or the Netherlands
Gay couples in Amsterdam and Eindhoven also reported being assaulted because of their sexuality over the weekend, according to Dutch media.
In some parts of the world, including India and some African countries, men commonly hold hands, taking it as a sign of friendship and respect.
The Netherlands was the first country in the world to legalise same-sex marriage in 2001.
The Dutch delegation at the UN in New York also took part
Two medical staff hold hands at an Utrecht hospital: "Because love (and care) is for everyone"
More about: #homophobia