The World Health Organization (WHO) announced that a child died from acute hepatitis of unknown origin that has been seen in at least 11 countries – namely in Europe and the United States – with 169 cases in children and young people, according to the organization's statement.
Cases have been reported in the United Kingdom (114), Spain (13), Israel (12), the U.S. (9), Denmark (6), Ireland (5), the Netherlands (4), Italy (4), Norway (2), France (2), Romania (1), and Belgium (1), a WHO statement said.
The hepatitis, an inflation of the liver, had raised speculation in the medical arena that the cases could be triggered by a new strain of adenovirus or even COVID-19.
Richard Pebody, Member of the WHO European Region's High Pathogen Threats Team, told Stat, a health news site broadcasting in the U.S., that although hepatitis cases were not high, it had bad results.
Emphasizing that it is not yet clear whether a new epidemic will emerge from mysterious hepatitis cases, Pebody said, "It would be good for WHO member countries to investigate."
COVID-19 has been reported in 20 of the cases, and 19 were detected with the coronavirus and adenovirus co-infection, said the world health group.
"While adenovirus is currently one hypothesis as the underlying cause, it does not fully explain the severity of the clinical picture," the WHO said.
Those with cases are aged 1 month to 16 years, and 17 children – approximately 10% – have needed liver transplantation, and at least one death has been reported.
Britain first reported an unexpected significant increase in cases of severe acute hepatitis of unknown origin in young, generally previously healthy children.
Many cases reported gastrointestinal symptoms, including abdominal pain, diarrhea and vomiting preceding presentation with severe acute hepatitis.
The common viruses that cause acute viral hepatitis – hepatitis viruses A, B, C, D and E – have not been detected in any of these cases.
Based on the currently available information, international travel or links to other countries have not been identified as factors.
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