They then used these cells to fertilise eggs and create hens which inherited those genes, meaning the birds were able to lay eggs containing the disease-fighting agent.
The scientists now have three hens whose eggs contain the drug, with the birds laying eggs almost daily, the report said.
The researchers plan to sell the drug to pharmaceutical companies, halving its price, so the firms can use it first as a research material, the newspaper said.
Consumers may have to wait a while, as Japan has strict regulations concerning the introduction of new or foreign pharmaceutical products, with screening processes that routinely take years to complete.
But the team hopes that the technological breakthrough will eventually help drive down the cost of the drug to 10 percent of its current price, the newspaper reported.
More about: #eggs